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RAP opportunity at National Institute of Standards and Technology     NIST

Protein Aggregation


Material Measurement Laboratory, Materials Science and Engineering Division

opportunity location
50.64.21.C0328 Gaithersburg, MD

NIST only participates in the February and August reviews.


name email phone
Steven David Hudson 240.688.7883
Paul Francis Salipante 301-975-2820


Microscopic fluid dynamics at surfaces lead to irreversible protein aggregation; this is a concern for biomanufacturing. Controlling temperature, interface chemistry and shear rate will help decouple the interplay between thermodynamics, interfacial adsorption, and hydrodynamic deformation and transport during the kinetics of protein aggregation. In-situ measurements of adsorption (structure and amount) and particle characterization will determine formation mechanisms.

key words
Protein solutions; Monoclonal antibodies; Interfacial adsorption; Optical microscopy; Microfluidics; Neutron scattering;


Citizenship:  Open to U.S. citizens
Level:  Open to Postdoctoral applicants


Base Stipend Travel Allotment Supplementation
$82,764.00 $3,000.00
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