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RAP opportunity at National Institute of Standards and Technology     NIST

Advanced Methods for Screening Human Stem Cell Function in 3D Tissue Scaffolds


Material Measurement Laboratory, Biosystems and Biomaterials Division

opportunity location
50.64.41.B7296 Gaithersburg, MD

NIST only participates in the February and August reviews.


name email phone
Carl George Simon 301.975.8574


Our goal is to develop advanced methods for assessing cell response to tissue-engineering scaffolds. Biomaterials are commonly used as 3D scaffolds and cells behave more physiologically when cultured in a 3D environment. This project will focus on the development of systematic, reliable methods for screening cell behavior during culture in scaffolds.  Methods may include advanced imaging modalities (3D methods), combinatorial/high-throughput methods, omics approaches, multivariate analyses and animal models (with collaborators at NIH).  Emphasis will be placed on 3D imaging and methods for assessing differentiation of human stem cells down desired lineages. The development of these techniques will provide the means to reliably screen tissue scaffolds to support cell function.


key words
Biomaterials; Cell differentiation; Hydrogel; Scaffold; Stem cell; Tissue engineering; Regenerative medicine; Stem cell;


Citizenship:  Open to U.S. citizens
Level:  Open to Postdoctoral applicants


Base Stipend Travel Allotment Supplementation
$82,764.00 $3,000.00
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