RAP opportunity at U.S. Army CCDC Chemical Biological Center CCDC CBC
Electrophysiological Characterization of Ion Channel Modulating Substances
Location
U.S. Army CCDC - Chemical Biological Center, Chemistry & Chemical Technology
| opportunity |
location |
|
| 11.01.01.C0274 |
Aberdeen Proving Ground, MD 210105423 |
Advisers
| name |
email |
phone |
|
| Kyle Philip Glover |
kyle.p.glover.civ@army.mil |
410.417.0298 |
Description
Automated whole cell patch clamping has allowed for the rapid and repeatable study of individual ion channels for drug developers and drug safety in the pharmacological industry. There is great potential for direct application of these methodologies to emerging threat compound(s) risk assessment. The objective of this research opportunity is to create or adapt methodologies currently in use by Pharma and other drug development pipelines, and optimize these methods for rapid toxicological assessment of chemical warfare agents and threat compounds. A successful proposal will incorporate expertise of electrophysiology, manual or automated, to accomplish the task of characterizing the effects of threat agents on ion channel receptor targets, be it through agonism, antagonism, or direct/indirect modulation.
key words
Electrophysiology; Ion Channels; Toxicity; Patch clamp;
Eligibility
Citizenship:
Open to U.S. citizens
Level:
Open to Postdoctoral and Senior applicants
Stipend
| Base Stipend |
Travel Allotment |
Supplementation |
|
| $83,592.00 |
$3,000.00 |
$5,000 Supplement for Doctorates in Engineering & Computer Science
$4,050 Supplement for each year of experience in the DTRA CBD-funded NRC tenure at CCDC. |
Experience Supplement
Postdoctoral and Senior awardees will receive an appropriately higher stipend based on the number of years of experience past their PhD.
|
Additional Benefits
Relocation
Awardees who reside more than 50 miles from their host laboratory and remain on tenure for at least six months are eligible for paid relocation to within the vicinity of their host laboratory.
Health insurance
A group health insurance program is available to awardees and their qualifying dependents in the United States.