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RAP opportunity at Air Force Science and Technology Fellowship Program     AF STFP

The Role of Biological Adaptations to Microgravity in Cellular Responses to Electroporation

Location

711th Human Performance Wing, RHD/Bioeffects Group

opportunity location
13.15.10.C1023 Fort Sam Houston, TX 78234

Advisers

name email phone
Zachary Andrew Steelman zachary.steelman.1@us.af.mil 713 299 3143

Description

The mission of the Air Force Research Laboratory’s Bioeffects Division (RHD) is to enable the maximum safe exploitation of the electromagnetic spectrum for DoD purposes.  This includes the study of the biological effects of pulsed electric fields (PEFs) which are commonly used for biological applications including electroporation (the permeabilization of the plasma membrane to deliver new DNA to the cell) as well as for disinfection and purification. 

With the standup of Space Force and to build scientific knowledge for future operational requirements, the DoD is interested in adapting current technologies to the unique environmental conditions of space, including microgravity.  Our lab has begun investigating how cellular adaptations to microgravity affect the endpoints of electroporation, with the goal of supporting resilient space operations through orbital biomanufacturing.

We are looking for a motivated postdoctoral researcher with an interest in developing microgravity cell culture models and applying them towards open questions in bioelectromagnetics.  The candidate may utilize existing microgravity models (rotating wall vessel, random positioning machine), or pursue the design of improved microgravity models which incorporate sensing, imaging, or external stimuli.  Project details and scope will be developed in consultation with the research mentor.  The ideal candidate will have a PhD in Biomedical Engineering, Biology, Electrical Engineering, Physics, or a related field.  Experience in cell culture methods, microscopy, and biological assays is considered a plus.  Knowledge of engineering design, electronics, and control systems will also be considered a plus.  Interested candidates should contact Dr. Zachary Steelman (zachary.steelman.1@us.af.mil) for more information and to submit a resume.

Keywords: Microgravity, electroporation, directed energy bioeffects, space, bioelectromagnetics

Relevant References:

[1]          E. Lastauskiene et al., International Journal of Astrobiology, vol. 18, pp. 405-411, (2019).

key words
Microgravity; electroporation; directed energy bioeffects; space; bioelectromagnetics

Eligibility

Citizenship:  Open to U.S. citizens
Level:  Open to Postdoctoral and Senior applicants

Stipend

Base Stipend Travel Allotment Supplementation
$95,000.00 $5,000.00

Experience Supplement:
Postdoctoral and Senior Associates will receive an appropriately higher stipend based on the number of years of experience past their PhD.

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