NRC Research and Fellowship Programs
Fellowships Office
Policy and Global Affairs

Participating Agencies

  sign in | print

RAP opportunity at National Institute of Standards and Technology     NIST

Oligonucleotide Analysis by Mass Spectrometry


Material Measurement Laboratory, Biomolecular Measurement Division

opportunity location
50.64.51.C0658 Gaithersburg, MD

NIST only participates in the February and August reviews.


name email phone
Mark Scott Lowenthal 301.975.8993
Trina Mouchahoir 240.314.6217


Robust analytical characterization of oligonucleotides is essential to the production of safe and consistent RNA-based products, and is a necessary part of a biomanufacturing design.  This opportunity focuses on developing advanced techniques in mass spectrometry for detecting, identifying, and quantifying oligonucleotides and impurities in various forms, with a focus on healthcare, therapeutics, and vaccines.  Available instrumentation includes high resolution mass spectrometry (QToF, QExactive, Orbitrap) and quantitative mass spectrometry (QQQ-MS) with liquid chromatography.  We encourage applicants who want to join a growing field and make an impact.

key words
oligonucleotides; RNA; mass spectrometry; LC-MS/MS; therapeutics; vaccines; CRISPR-Cas; mRNA


Citizenship:  Open to U.S. citizens
Level:  Open to Postdoctoral applicants


Base Stipend Travel Allotment Supplementation
$82,764.00 $3,000.00
Copyright © 2024. National Academy of Sciences. All rights reserved.Terms of Use and Privacy Policy