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RAP opportunity at National Institute of Standards and Technology     NIST

Macromolecular Separation Science


Material Measurement Laboratory, Chemical Sciences Division

opportunity location
50.64.61.B8006 Gaithersburg, MD

NIST only participates in the February and August reviews.


name email phone
Andre Michael Striegel 301.975.3159


Research focuses on the development and application of advanced multi-detector separation science techniques. Topics include characterizing the phase space inhabited by complex macromolecules and blends, nano/microplastics, nanoparticles, and carbohydrates. This will be done primarily using size-based separation methods such as SEC, AF4, and HF5, in conjunction with interaction polymer chromatography techniques such as i-GPEC and LCCC, coupled to a variety of on-line detection methods, including MALS, QELS, VISC, ICP-MS, Raman, etc. Exploring the fundamentals of the separation and detection methods is also part of this opportunity.



Striegel AM: Absolute molar mass determination in mixed solvents. 2. SEC/MALS/DRI in a mix of two "nearly-isovirial" solvents. Analytica Chimica Acta 1231:340369, 2022

Striegel AM: Method development in interaction polymer chromatography. Trends in Analytical Chemistry 130:115990, 2020

Pitkänen L, Montoro Bustos AR, Murphy KE, Winchester MR, Striegel AM: Quantitative characterization of gold nanoparticles by size-exclusion and hydrodynamic chromatography, coupled to inductively coupled plasma mass spectrometry and quasi-elastic light scattering. Journal of Chromatography A 1511: 59-67, 2017

Pitkänen L, Striegel AM: Polysaccharide characterization by hollow-fiber flow field-flow fractionation with on-line multi-angle static light scattering and differential viscometry. Journal of Chromatography A 1380:146-155, 2015

key words
Separation science; Multiple detection; Multi-dimensional; Macromolecules; Polymers, Carbohydrates; Nanoparticles; Polysaccharides; Liquid chromatography;


Citizenship:  Open to U.S. citizens
Level:  Open to Postdoctoral applicants


Base Stipend Travel Allotment Supplementation
$82,764.00 $3,000.00
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