NIST only participates in the February and August reviews.
Research focuses on the development and application of advanced multi-detector separation science techniques. Topics include characterizing the phase space inhabited by complex macromolecules and blends, nano/microplastics, nanoparticles, and carbohydrates. This will be done primarily using size-based separation methods such as SEC, AF4, and HF5, in conjunction with interaction polymer chromatography techniques such as i-GPEC and LCCC, coupled to a variety of on-line detection methods, including MALS, QELS, VISC, fluorescence, ICP-MS, Raman, etc. Exploring the fundamentals of the separation and detection methods is also part of this opportunity.
References
Striegel AM: On-line coupling of hollow-fiber flow field-flow fractionation and depolarized multi-angle static light scattering (HF5/D-MALS). Proof of principle. Journal of Chromatography A 1739:465115 2024
Striegel AM: Absolute molar mass determination in mixed solvents. 2. SEC/MALS/DRI in a mix of two "nearly-isovirial" solvents. Analytica Chimica Acta 1231:340369, 2022
Striegel AM: Method development in interaction polymer chromatography. Trends in Analytical Chemistry 130:115990, 2020
Pitkänen L, Montoro Bustos AR, Murphy KE, Winchester MR, Striegel AM: Quantitative characterization of gold nanoparticles by size-exclusion and hydrodynamic chromatography, coupled to inductively coupled plasma mass spectrometry and quasi-elastic light scattering. Journal of Chromatography A 1511: 59-67, 2017
Pitkänen L, Striegel AM: Polysaccharide characterization by hollow-fiber flow field-flow fractionation with on-line multi-angle static light scattering and differential viscometry. Journal of Chromatography A 1380:146-155, 2015
Separation science; Multiple detection; Multi-dimensional; Macromolecules; Polymers, Carbohydrates; Nanoparticles; Polysaccharides; Liquid chromatography;