RAP opportunity

NRC Research and Fellowship Programs

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Participating Agencies

RAP opportunity at National Institute of Standards and Technology NIST

Structure-Function Determination of Membrane Proteins

Location

Physical Measurement Laboratory, Microsystems and Nanotechnology Division

opportunity	location

50.68.02.B7578	Gaithersburg, MD 20899

NIST only participates in the February and August reviews.

Advisers

name	email	phone

Joseph William Robertson	joseph.robertson@nist.gov	301.975.2506

Description

Structures of membrane proteins have proven difficult to obtain using X-ray crystallography. To address this issue, we are using neutron reflectometry, small-angle neutron scattering, surface plasmon resonance, and electrophysiology to determine the structure, function, and mechanism of assembly of membrane proteins. Current molecules of interest include, but are not limited to, bacterial toxins that are biowarfare agents (e.g., anthrax, clostridium).

References

McGillivray DJ, et al: Biophysical Journal 96: 1547, 2009

McGillivray DJ, et al: Biointerphases 2: 21, 2007

key words

Membrane protein; Structure; Function; Neutron reflectometry; Electrochemistry; Surface plasmon resonance;

Eligibility

Citizenship: Open to U.S. citizens

Level: Open to Postdoctoral applicants

Stipend

Base Stipend	Travel Allotment	Supplementation

$82,764.00	$3,000.00