Opportunity at National Institute of Standards and Technology NIST
Drug Toxicity Measurements with Tissues-on-chips and Microphysiologic Systems
Physical Measurement Laboratory, Microsystems and Nanotechnology Division
||Gaithersburg, MD 20899
Please note: This Agency only participates in the February and August reviews.
|Mandy Brigitte Esch
Postdoctoral research opportunities are available for developing tissues-on-chips and multi-organ microphysiological systems (MPS) that realize reliable and accurate drug testing of new drug candidates. Our laboratory has developed microphysiological systems that operate with small amounts of recirculating cell culture medium (Lab on a Chip 16(14): 2719-2729, 2016, and Microphysiol Syst. 2020 Jun; 4: 10.21037/mps-19-8) that will make toxic metabolite detection more sensitive. Recent work includes a new, pumpless liver/heart system. NRC postdocs can propose to work on optimizing MPS designs (potentially with integrated, microfabricated sensors), developing new tissues-on-chips, developing MPS for new organ combinations, and testing drug candidates in collaboration with NIH with any of the developed devices.
Body-on-a-chip; Organ-on-a-chip; Tissues-on-chips, Microfluidics, microphysiologic systems; MPS; Biosensors; Nanofabrication; Liver; Toxicity; Drug;
Open to U.S. citizens
Open to Postdoctoral applicants