RAP opportunity at U.S. Army Medical Research & Materiel Command AMRMC
Mosquito Factors to Improve Models and Therapeutics for Mosquito-Borne Viruses
Location
Walter Reed Army Institute of Research, Infectious Diseases-Viral Diseases Branch
opportunity |
location |
|
97.15.12.C0586 |
Silver Spring, MD 20910 |
Advisers
name |
email |
phone |
|
Michael Kevin McCracken |
michael.k.mccracken.civ@health.mil |
301.319.3026 |
Description
Research will be conducted in the Preclinical Research Section of the Medical Countermeasures Department within the Viral Diseases Branch of the Walter Reed Army Institute of Research (WRAIR). The proposed research will focus on exploring mosquito factors with the potential to influence transmission, establishment of infection within the vertebrate, and/or pathogenesis of disease, with the overall goal of improving challenge models of medically important mosquito-borne viruses and/or improving vaccine platforms by targeting novel antigens. Potential projects could include: 1) determining titers and any associated variability of expectorated viruses during blood-feeding, 2) characterizing expectorated substances during mosquito blood-feeding, such as individual mosquito salivary proteins, 3) characterizing humoral and cellular immunity to expectorated substances in extant samples from ongoing cohort studies, 4) development of assays for surveillance of vector exposure.
key words
mosquito; virus; flavivirus; alphavirus; saliva; protein expression; serology; vaccinology; challenge models; therapeutics;
Eligibility
Citizenship:
Open to U.S. citizens, permanent residents and non-U.S. citizens
Level:
Open to Postdoctoral and Senior applicants
Stipend
Base Stipend |
Travel Allotment |
Supplementation |
|
$74,000.00 |
$4,000.00 |
|
Experience Supplement
Postdoctoral and Senior awardees will receive an appropriately higher stipend based on the number of years of experience past their PhD.
|
Additional Benefits
Relocation
Awardees who reside more than 50 miles from their host laboratory and remain on tenure for at least six months are eligible for paid relocation to within the vicinity of their host laboratory.
Health insurance
A group health insurance program is available to awardees and their qualifying dependents in the United States.