RAP opportunity at National Institute of Standards and Technology NIST
Oligonucleotide Analysis by Mass Spectrometry
Location
Material Measurement Laboratory, Biomolecular Measurement Division
opportunity |
location |
|
50.64.51.C0658 |
Gaithersburg, MD |
NIST only participates in the February and August reviews.
Advisers
name |
email |
phone |
|
Mark Scott Lowenthal |
mark.lowenthal@nist.gov |
301.975.8993 |
Trina Mouchahoir |
trina.mouchahoir@nist.gov |
240.314.6217 |
Description
Robust analytical characterization of oligonucleotides is essential to the production of safe and consistent RNA-based products, and is a necessary part of a biomanufacturing design. This opportunity focuses on developing advanced techniques in mass spectrometry for detecting, identifying, and quantifying oligonucleotides and impurities in various forms, with a focus on healthcare, therapeutics, and vaccines. Available instrumentation includes high resolution mass spectrometry (QToF, QExactive, Orbitrap) and quantitative mass spectrometry (QQQ-MS) with liquid chromatography. We encourage applicants who want to join a growing field and make an impact.
key words
oligonucleotides; RNA; mass spectrometry; LC-MS/MS; therapeutics; vaccines; CRISPR-Cas; mRNA
Eligibility
Citizenship:
Open to U.S. citizens
Level:
Open to Postdoctoral applicants
Stipend
Base Stipend |
Travel Allotment |
Supplementation |
|
$82,764.00 |
$3,000.00 |
|
|